At least 15 people have died as a result of extreme weather and flooding in Kentucky, West Virginia, and Georgia, according to state officials this week.

Many counties in Kentucky received multiple inches of rain over the weekend, and more than 1,000 water rescues were conducted. Hundreds of roads have been closed across the state due to the storm’s impacts, and emergency shelters have opened across the state for people without access to power or heat.

More winter weather is expected to sweep through the region on Tuesday, bringing significant amounts of snow, with some areas of Kentucky seeing as much as eight inches, and parts of Virginia may see as much as six inches.

In response to medical needs resulting from the storm, Direct Relief has offered support to multiple organizations, including the Kentucky Primary Care Association, as well as health centers and free clinics in the region.

The organization will respond as needs become known.